2. Signaling Pathways
  3. GPCR/G Protein
    Neuronal Signaling
  4. Orexin Receptor (OX Receptor)
  5. Orexin Receptor (OX Receptor) Inhibitor

Orexin Receptor (OX Receptor) Inhibitor

Orexin Receptor (OX Receptor) Isoform Comparison

Orexin Receptor (OX Receptor) Inhibitors (9):

Cat. No. Product Name Effect Purity
  • HY-P99836
    Cudarolimab
    		Inhibitor
    Cudarolimab (IBI101) is a completely human anti-OX40 (CD134, a co stimulating molecule expressed by activated immune cells) antibody. Cudarolimab inhibits the binding of OX40 to its ligand OX40L. Cudarolimab has antitumor activity and can be used in cancer related research.
  • HY-123176
    GYKI-13380
    		Inhibitor
    GYKI-13380 is an appetite suppressant. GYKI-13380 has the potential for the research of neurology diseases.
  • HY-P991338
    MEDI-6469
    		Inhibitor
    MEDI-6469 is a human monoclonal antibody (mAb) targeting TNFRSF4/OX40/CD134. MEDI-6469 targets the OX40 receptor on activated T cells to enhance the immune response against cancer cells..
  • HY-P991335
    BAT6026
    		Inhibitor
    BAT6026 is a human monoclonal antibody (mAb) targeting TNFRSF4/OX40/CD134. BAT6026 significantly reduces Treg cells and increased CD8+ T cells in tumor.
  • HY-P991339
    ZL-1101
    		Inhibitor
    ZL-1101 is a human monoclonal antibody (mAb) targeting TNFRSF4/OX40/CD134.
  • HY-P990479
    Anti-OX2R/CD200R1 Antibody
    		Inhibitor
    Anti-OX2R/CD200R1 Antibody is a CHO-expressed human antibody that targets OX2R/CD200R1. The predicted molecular weight (MW) of Anti-OX2R/CD200R1 Antibody is 146.58 kDa. The isotype control for Anti-OX2R/CD200R1 Antibody can refer to Human IgG4 kappa, Isotype Control (HY-P99003).
  • HY-P991337
    YH-002
    		Inhibitor
    YH-002 is a human IgG1 monoclonal antibody (mAb) targeting TNFRSF4/OX40/CD134. YH-002 binds to OX40 by mimicking the function of OX40L.
  • HY-149014
    OX2R-IN-1
    		Inhibitor
    OX2R-IN-1 (compound 15) is a low cytotoxicity profile OX2R-IN-1 antagonist (a potential OX2R binder) with an IC50 value of 484 μM. OX2R-IN-1 (compound 15) can cross the BBB into the brain with a short half-life.
  • HY-P991334
    INCAGN1949
    		Inhibitor
    INCAGN1949 is a human IgG1 monoclonal antibody (mAb) targeting TNFRSF4/OX40/CD134. INCAGN1949 selectively deplete intratumoral regulatory T cells.